Lixy you said your sis was on several meds,get a list of them and take it to a pharmacist to see if some are reacting with others.We had to do this with my mother- in- law she was taking what the Dr told her to but it was making her higher than a kite due to a couple of drugs reacting with each other, acting like a narcotic,Taken alone they were fine,just not together. It costs nothing and its a place to start.I will add you and family to the prayer list.

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The mind never forgets what the hands have learned